Magnesium Glycinate vs Bisglycinate: Key Differences
By BioSchwartz | Superior Standards in Dietary Supplements® | Published: 2026-10-17
Category: Comparisons
Compare magnesium glycinate and bisglycinate forms to find the best supplement for your needs, based on absorption, dosage, and purity.
Quick answer
Magnesium glycinate and magnesium bisglycinate are both highly absorbable forms of magnesium, but bisglycinate is a purer, more concentrated version that is easier on the stomach and less likely to cause laxative effects. For most people, magnesium bisglycinate offers the best balance of absorption and tolerability, while magnesium glycinate is a solid, more budget-friendly option.
What is Magnesium Glycinate?
Magnesium glycinate is a chelated form of magnesium bound to the amino acid glycine. This bond allows for efficient absorption in the digestive tract, making it a popular choice for those seeking a gentle magnesium supplement. BioSchwartz's Magnesium Glycinate Capsules deliver 500 mg of magnesium glycinate per serving, providing 100 mg of elemental magnesium.
What is Magnesium Bisglycinate?
Magnesium bisglycinate is a more refined form where each magnesium molecule is bonded to two glycine molecules, creating an even more stable and bioavailable compound. BioSchwartz's Magnesium Bisglycinate Capsules offer a pure formula free from binders, fillers, and chemical additives, designed for optimal absorption without the laxative effect often associated with other magnesium forms.
Trade-offs to consider
- Absorption and purity: Bisglycinate offers a purer, more concentrated form with no binders or fillers, potentially leading to better absorption for some individuals. Glycinate is still highly absorbable but may contain added ingredients. Choose bisglycinate if purity is your top priority.
- Stomach sensitivity: Bisglycinate is specifically designed to be easy on the stomach with no laxative effect, making it a better choice for those who experience digestive discomfort with other magnesium forms. Glycinate is also gentle but may not be as well-tolerated for very sensitive individuals. If you have a sensitive stomach, bisglycinate is the safer bet.
- Cost and value: Magnesium glycinate is typically more budget-friendly, offering a lower price per capsule. Bisglycinate comes at a higher cost but provides a more refined, pure product in a larger count (360 capsules vs 240). Opt for glycinate if you want a cost-effective daily dose; bisglycinate for a premium, long-lasting supply.
Product facts at a glance
- Magnesium Bisglycinate Capsules, 360ct: 360 Easy-to-swallow mini capsules: BioSchwartz has developed a pure magnesium bisglycinate supplement in tiny, easy-to-swallow mini-caps! This formula is free of binders, fillers and other chemical additives • Easy on the stomach with no laxative effect: This vegan & vegetarian formula comes in easy to swallow tiny capsules for optimal absorption and bioavailability while being well-tolerated without the… The purity and small capsule size make it ideal for those with sensitive stomachs or who dislike swallowing large pills.
- Magnesium Glycinate Capsules, 240ct: • Ultra Pure Magnesium Glycinate 500mg Capsules: Our vegan safe magnesium supplement contains 500mg high potency magnesium glycinate providing 100mg pure elemental magnesium, the easiest form of magnesium for the body to absorb and benefit from • Magnesium for Sleep Calm Bone Support and More: Magnesium is an essential mineral that helps support key processes in the body including muscle health, bone mineralization,… With a clear elemental magnesium content, it's easy to track your daily intake, and the glycinate form is well-tolerated for sleep and muscle recovery.
Which one fits you?
Best for
- Those seeking maximum purity and stomach comfort – choose Magnesium Bisglycinate Capsules.
- Budget-conscious buyers who still want high absorption – choose Magnesium Glycinate Capsules.
Not for
- Anyone who needs a very high elemental magnesium dose per capsule – bisglycinate's elemental content isn't specified, so glycinate (100 mg elemental per capsule) may be easier to track.

